Head to Head

AGIO vs ALNY: which is the better buy in 2026?

Agios Pharmaceuticals, Inc.

NASDAQ:AGIO

90/100 Compass
True NorthAccumulate$2.6B

A rare disease franchise turning into a multi-indication PK activator platform, with sickle cell as the swing factor.

Full AGIO analysis

Alnylam Pharmaceuticals

NASDAQ:ALNY

90/100 Compass
True NorthAccumulate$42.9B

RNAi's first profitable platform company is trading near its 52-week low while its pipeline has never been broader or more valuable.

Full ALNY analysis

Factor by factor

FactorAGIOALNY
Revenue Growth9898
Profitability1877
Valuation7420
Momentum8431
Theme Purity5899
Moat5049
Catalysts6399
Market Position4852

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Frequently asked questions

Is AGIO or ALNY the better buy in 2026?

AGIO and ALNY are neck and neck at 90/100 on the Compass right now. The better fit depends on which factors matter most to you.

How does Alexandria compare AGIO and ALNY?

Each company is scored 1-100 on eight factors: revenue growth, profitability, valuation, momentum, theme purity, moat, catalysts, and market position. The Compass Score is the composite, and the comparison below shows where each name wins factor by factor.

Compass Scores are proprietary editorial research from publicly available data, not investment advice or a recommendation regarding any security. Rankings update weekly.